Anti-atherosclerotic peptide delivery from a photocrosslinkable biodegradable network.

Abstract

A water-soluble, 19-mer peptide fragment of serum amyloid A called MFFD is being examined as a possible treatment for atherosclerosis. As a means of administering this drug in a sustained fashion through subcutaneous implantation, a biodegradable network formulation was prepared. The formulation consisted of 1000 and 4000Da alpha,omega-diacrylate oligo(d,l… (More)
DOI: 10.1016/j.ijpharm.2009.12.030

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