Anti-atherosclerotic activity of catechins depends on their stereoisomerism.

@article{Mika2015AntiatheroscleroticAO,
  title={Anti-atherosclerotic activity of catechins depends on their stereoisomerism.},
  author={Magdalena Mika and Renata B. Kostogrys and Magdalena Franczyk-Żar{\'o}w and Agnieszka Wikiera and Edyta Maślak},
  journal={Atherosclerosis},
  year={2015},
  volume={240 1},
  pages={125-30}
}
In terms of stereochemistry, catechins are divided into two groups: (-) epi forms (2R, 3R) and (-) forms (2S, 3R). Most of the catechins present in green tea are (-) epi forms (2R, 3R). Under the influence of high temperatures, in anaerobic conditions, as a result of epimerization the proportion of the (-) form (2S, 3R) increases. The data indicate that the presence of thermally modified catechins in the diet more efficiently reduces the development of atherosclerosis in apoE knockout mice than… CONTINUE READING