Anti-asthmatic effects of matrine in a mouse model of allergic asthma.

@article{Fu2014AntiasthmaticEO,
  title={Anti-asthmatic effects of matrine in a mouse model of allergic asthma.},
  author={Qiang Fu and Jing Wang and Zhanqing Ma and Shiping Ma},
  journal={Fitoterapia},
  year={2014},
  volume={94},
  pages={183-9}
}
The aim of the study was to investigate the anti-asthmatic effects of matrine and the possible mechanisms. Asthma model was established by ovalbumin-induced. A total of 50 mice were randomly assigned to five experimental groups: control, model, dexamethasone (2 mg/kg) and matrine (50 mg/kg, 100 mg/kg). Airway resistance (Raw) was measured, histological studies were evaluated by the hematoxylin and eosin (HE) staining, interleukin-4 (IL-4) and interleukin-13 were evaluated by enzyme-linked… CONTINUE READING