Anti-arthritic active fraction of Capparis spinosa L. fruits and its chemical constituents.
@article{Feng2011AntiarthriticAF, title={Anti-arthritic active fraction of Capparis spinosa L. fruits and its chemical constituents.}, author={Xiaolu Feng and Jincai Lu and Hailiang Xin and Lei Zhang and Yuliang Wang and Kexuan Tang}, journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan}, year={2011}, volume={131 3}, pages={ 423-9 } }
The aim of this study was to ascertain the anti-arthritic active fraction of Capparis spinosa L. (Capparidaceae) fruits and its chemical constituents. The adjuvant arthritic rat model was developed to evaluate the anti-arthritic effects of different fractions of ethanol extraction from C. spinosa L. The fraction eluted by ethanol-water (50:50, v/v) had the most significant anti-arthritic activity. The chemical constituents of this fraction were therefore studied; seven known compounds were…
Figures and Tables from this paper
48 Citations
Capparis spinosa L.: a natural source of pharmaceuticals
- Biology
- 2018
Biological activities of some compounds isolated from C. spinosa reveal important antimicrobial, antioxidative, anti-inflammatory, antidiabetic, immunomodulatory, and antiviral properties.
Investigation for anti-inflammatory and anti-thrombotic activities of methanol extract of Capparis ovata buds and fruits.
- Medicine, BiologyJournal of ethnopharmacology
- 2012
Acute effect of Capparis spinosa root extracts on rat articular pain.
- MedicineJournal of ethnopharmacology
- 2016
THE CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL EFFECTS OFCAPPARIS SPINOSA -AN OVERVIEW
- Chemistry, Biology
- 2015
The present review will designed to highlight the chemical constituents and the pharmacological effects of Capparis spinosa.
Antiarthritic activity of hydroalcoholic seed extract of Cassia tora Linn.
- Chemistry
- 2013
The hydroalcoholic (70%) extract of seeds of Cassia tora (at different doses 100, 250 and 500 mg/kg, body weight) was screened for antiarthritic activity. In Complete freund's adjuvant (CFA) induced…
Chemical investigation, the antibacterial and antifungal activity of different parts of Capparis spinosa extracts
- 2020
The chemical profiles of the present bioactive responsible for the pharmacological effects of C. spinosa are detail and the presence of polyphenols in different parts of the plant as well as their antimicrobial effects are experimentally demonstrated.
Comparison of Gastric-ulcerogenecity Effect of Methanolic Extract of Capparis spinosa and Indomethacin in Rat
- MedicineJundishapur Journal of Natural Pharmaceutical Products
- 2021
The results indicated that percolated extract of C. Spinosa administered orally in antinociceptive dosage and even 2,4 and 8 folds did not cause a gastric ulcer compared to indomethacin, and seems to be a suitable choice for more pharmacological and toxicology examinations to use as analgesic.
REVIEW ON ETHNOBOTANICAL STUDIES OF NUTRACEUTICAL PLANT: CAPPARIS SPINOSA L. (CAPER)
- Medicine
- 2016
This review attempts to encompass the available literature on C. spinosa with respect to its pharmacognostic characters, chemical constituents, nutritional characters, various pharmacological activities, traditional uses, and modern use.
Isolation and Identification of Alkaloidic Extract of Capparis spinosaL Buds and Study of Its Cytoxicity and Antibacterial Activity.
- Biology, Chemistry
- 2016
Antibacterial activity of alkaloidic extract was investigated against some pathogenic bacteria which represented by Escherichia coli and Staphylococcus aureus and the concentration of (250 mg/ml) was found to be the maximal inhibitory concentration against both pathogenicacteria.
Pharmacological Evaluation of Anti-Inflammatory Activity of Aqueous Extract of the Root Bark of Capparis Erythrocarpos
- Medicine
- 2015
This study verified claims in folklore medicine that the aqueous extract of the root bark of Capparis erythrocarpos has anti-inflammatory activity, as well as to ascertain its safety in animal models.
References
SHOWING 1-10 OF 15 REFERENCES
Antihepatotoxic activity of p-methoxy benzoic acid from Capparis spinosa.
- Chemistry, BiologyJournal of ethnopharmacology
- 1999
Evaluation of extracts and isolated fraction from Capparis spinosa L. buds as an antioxidant source.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2002
The findings indicate that the antioxidant efficiency of the methanolic extract may be attributed to its phenolic content, and the antioxidant activity was maintained after removal of glucosinolates, confirming that these compounds do not interfere with the antioxidant properties of the extract.
Cloricromene, a coumarine derivative, protects against collagen‐induced arthritis in Lewis rats
- Biology, MedicineBritish journal of pharmacology
- 2000
This study provides the first evidence that cloricromene, a coumarine derivative, attenuates the degree of chronic inflammation and tissue damage associated with collagen‐induced arthritis in the rat.
Chemical composition of Capparis spinosa fruit
- ChemistryChemistry of Natural Compounds
- 2007
The known compounds cappariloside A and stachydrin, an adenosine nucleoside, and for the first time from plants of the Capparidaceae family the known compounds hypoxanthine and uracil were isolated…
Plants used for the treatment of diabetes in Israel.
- Biology, MedicineJournal of ethnopharmacology
- 1987
Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats.
- BiologyJournal of ethnopharmacology
- 2005
Suppressive effects of bee venom on the immune responses in collagen-induced arthritis in rats.
- Biology, MedicinePhytomedicine : international journal of phytotherapy and phytopharmacology
- 2008
Phytotherapy of hypertension and diabetes in oriental Morocco.
- MedicineJournal of ethnopharmacology
- 1997