Anti-arrhythmic Medication Propafenone a Potential Drug for Alzheimer's Disease Inhibiting Aggregation of Aβ: In Silico and in Vitro Studies

Abstract

Alzheimer's disease (AD) is the most common form of dementia caused by the formation of Aβ aggregates. So far, no effective medicine for the treatment of AD is available. Many efforts have been made to find effective medicine to cope with AD. Curcumin is a drug candidate for AD, being a potent anti-amyloidogenic compound, but the results of clinical trials… (More)
DOI: 10.1021/acs.jcim.6b00029

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@article{Ngo2016AntiarrhythmicMP, title={Anti-arrhythmic Medication Propafenone a Potential Drug for Alzheimer's Disease Inhibiting Aggregation of Aβ: In Silico and in Vitro Studies}, author={Son Tung Ngo and Shang-Ting Fang and Shu-Hsiang Huang and Chao-Liang Chou and Pham Dinh Quoc Huy and Mai Suan Li and Yi-Cheng Chen}, journal={Journal of chemical information and modeling}, year={2016}, volume={56 7}, pages={1344-56} }