Anti-apoptotic role of retinoic acid in the inner ear of noise-exposed mice.

@article{Ahn2005AntiapoptoticRO,
  title={Anti-apoptotic role of retinoic acid in the inner ear of noise-exposed mice.},
  author={Joong Ho Ahn and Hun Hee Kang and Young-Jin Kim and Jong Woo Chung},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={335 2},
  pages={485-90}
}
Exposure to loud noise can induce temporary or permanent hearing loss, and acoustic trauma is the major cause of hearing impairment in industrial nations. However, the mechanisms underlying the death of hair cells after acoustic trauma remain unclear. In addition to its involvement in cellular stress and apoptosis, the c-Jun N-terminal kinase (JNK), a member of the mitogen-activated protein kinase family, is involved in cell survival, transformation, embryonic morphogenesis, and differentiation… CONTINUE READING

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