Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody.

@article{Matsuda1994AntiannexinVA,
  title={Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody.},
  author={Juzo Matsuda and Nobuyuki Saitoh and Kengo Gohchi and Moritaka Gotoh and Masao Tsukamoto},
  journal={American journal of hematology},
  year={1994},
  volume={47 1},
  pages={56-8}
}
We investigated anti-annexin V antibody (aANX) in patients with systemic lupus erythematosus (SLE), and correlated to positivity with lupus anticoagulant (LA)/anticardiolipin antibody (aCL). aANX was positive in 12/47 SLE patients (26%), including 7 with beta 2-glycoprotein 1 (GPI)-dependent aANX. The positivity of aANX was higher in patients with aCL (19%) and LA/aCL (50%) than in those without LA/aCL (10%). From these results, it is concluded that aANX is an autoantibody closely related to LA… CONTINUE READING

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