Anti-angiogenic quassinoid-rich fraction from Eurycoma longifolia modulates endothelial cell function.

  title={Anti-angiogenic quassinoid-rich fraction from Eurycoma longifolia modulates endothelial cell function.},
  author={Omar Saeed Ali Al-Salahi and Chan Kit-Lam and Amin Malik Shah Abdul Majid and Fouad Saleih Resq Al-Suede and Sultan Ayesh Mohammed Saghir and Wan Zaidah Abdullah and Mohamed B. Khadeer Ahamed and Narazah Mohd Yusoff},
  journal={Microvascular research},
Targeting angiogenesis could be an excellent strategy to combat angiogenesis-dependent pathophysiological conditions such as cancer, rheumatoid arthritis, obesity, systemic lupus erythematosus, psoriasis, proliferative retinopathy and atherosclerosis. Recently a number of clinical investigations are being undertaken to assess the potential therapeutic application of various anti-angiogenic agents. Many of these angiogenesis inhibitors are directed against the functions of endothelial cells… CONTINUE READING
Highly Cited
This paper has 24 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 11 extracted citations


Publications referenced by this paper.
Showing 1-10 of 56 references

Eurycomanone induces apoptosis through the up-regulation of p53 in human cervical carcinoma cells

N. Mahfudh, A.H.L. Pihie
J. Cancer Mol • 2008
View 7 Excerpts
Highly Influenced

30–39 standardization of manufactured batches of Eurycoma longifolia Jack. extract as antimalarial medicaments

O.S.A. Al-Salahi
Microvascular Research • 2013

In vitro anti-Toxoplasma gondii activity of root extract/fractions of Eurycoma longifolia Jack

N Kavitha
BMC Complement. Altern. Med • 2012

Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe Merr

Nassar, Z.D
Cancer Cell Int • 2011

Developmental and pathological angiogenesis.

Annual review of cell and developmental biology • 2011
View 3 Excerpts

Similar Papers

Loading similar papers…