Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.

@article{Song2004AntiangiogenicAI,
  title={Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.},
  author={Yun Seon Song and Sun-Hyoung Kim and J. M. C{\'e}sar de S{\'a} and Changbae Jin and Chang-Jin Lim and Eun-Hee Park},
  journal={Journal of ethnopharmacology},
  year={2004},
  volume={90 1},
  pages={
          17-20
        }
}
Fresh fruit bodies of Ganoderma lucidum were extracted with 70% ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. 
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