Anti-anginal therapy and quality of life. A comparison of the effects of transdermal nitroglycerin and long-acting oral nitrates.

@article{Nissinen1991AntianginalTA,
  title={Anti-anginal therapy and quality of life. A comparison of the effects of transdermal nitroglycerin and long-acting oral nitrates.},
  author={Aulikki Nissinen and Ingela K Wiklund and Tyson J Lahti and Juha Akkila and Aimee Wilson and Michael F. Wahl and Pekka M Puska},
  journal={Journal of clinical epidemiology},
  year={1991},
  volume={44 9},
  pages={989-97}
}
A total of 112 male patients with severe effort-induced angina pectoris (New York Heart Association functional classes II and III) participated in a randomized open trial consisting of a 6 month phase with 3 month treatment cross-overs. The aim of the study was to compare the effect of transdermal nitroglycerin (TN) patches and long-acting oral nitrates (LAON) on quality of life (QL). During the cross-over period 30 patients (20 on TN and 10 on LAON) withdrew from the study, over half of them… CONTINUE READING