Anti-alpha-enolase autoantibodies are down-regulated in advanced cancer patients.

  title={Anti-alpha-enolase autoantibodies are down-regulated in advanced cancer patients.},
  author={Nianhao Shih and Hsing-Liang Lai and G. -t. Chang and Hsien-Chih Lin and Yu-Chung Wu and Jacqueline Ming Liu and Ko-Jiunn Liu and Szu-Wen Tseng},
  journal={Japanese journal of clinical oncology},
  volume={40 7},
OBJECTIVE Elevation of serum autoantibodies to alpha-enolase (ENO1) is often seen in inflammation diseases. However, it is unclear whether the levels of serum ENO1 autoantibodies could be affected during tumor progression. Hence, we attempted to determine the relative serum ENO1 autoantibody levels in healthy individuals and various stages of patients with lung and breast cancers. METHODS Sera were obtained from 99 normal individuals, 21 patients with non-cancer-associated diseases and 178… CONTINUE READING


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