Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice.

@article{Meotti2006AntiallodynicPO,
  title={Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice.},
  author={Fl{\'a}via Carla Meotti and Fabiana Cristina Missau and Juliano Ferreira and Moacir Geraldo Pizzolatti and Cristina Mizuzaki and Cristina Wayne Nogueira and Adair Roberto Soares dos Santos},
  journal={Biochemical pharmacology},
  year={2006},
  volume={72 12},
  pages={1707-13}
}
The aim of the present study was to investigate the effects of myricitrin, a flavonoid with anti-inflammatory and antinociceptive action, upon persistent neuropathic and inflammatory pain. The neuropathic pain was caused by a partial ligation (2/3) of the sciatic nerve and the inflammatory pain was induced by an intraplantar (i.pl.) injection of 20 microL of complete Freund's adjuvant (CFA) in adult Swiss mice (25-35 g). Seven days after sciatic nerve constriction and 24 h after CFA i.pl… CONTINUE READING

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