Anti-allergic inflammatory effect of vanillic acid through regulating thymic stromal lymphopoietin secretion from activated mast cells.

@article{Jeong2018AntiallergicIE,
  title={Anti-allergic inflammatory effect of vanillic acid through regulating thymic stromal lymphopoietin secretion from activated mast cells.},
  author={Hyun-Ja Jeong and Sun-Young Nam and Hee-Yun Kim and Mu Hyun Jin and Mi hye Kim and Seok Seon Roh and Hyung-Min Kim},
  journal={Natural product research},
  year={2018},
  volume={32 24},
  pages={
          2945-2949
        }
}
Vanillic acid, which is well known as a benzoic acid derivative, has been used as a flavouring agent. Currently, we ascertained the therapeutic potential action of vanillic acid on allergic inflammatory reaction in human mast cell line, HMC-1. Treatment with vanillic acid resulted in a significant decrease in levels of thymic stromal lymphopoietin and pro-inflammatory cytokines compared to phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-treated HMC-1 cells. In PMACI… CONTINUE READING

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