Anti-allergic constituents in the culture medium ofGanoderma lucidum. (II) The inhibitory effect of cyclooctasulfur on histamine release

@article{Tasaka1988AntiallergicCI,
  title={Anti-allergic constituents in the culture medium ofGanoderma lucidum. (II) The inhibitory effect of cyclooctasulfur on histamine release},
  author={Kenji Tasaka and Mitsunobu Mio and Keiji Izushi and Masaaki Akagi and Toshiyuki Makino},
  journal={Agents and Actions},
  year={1988},
  volume={23},
  pages={157-160}
}
For centuries,Ganoderma lucidum has been used in Oriental medicine for the treatment of chronic bronchitis. Sequential fractions of the culture medium of this plant revealed that one of the active constitutents was cyclooctasulfur. The latter effectively inhibited hsitamine release from rat peritoneal mast cells and impeded45Ca uptake into these cells without affecting the cyclic AMP content. SDS-PAGE analysis indicated that cyclooctasulfur induced some changes in protein bands obtained from… CONTINUE READING

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