Anti-agrin staining is absent at abandoned synaptic sites of frog neuromuscular junctions.

@article{Werle1996AntiagrinSI,
  title={Anti-agrin staining is absent at abandoned synaptic sites of frog neuromuscular junctions.},
  author={Michael J. Werle and A M Sojka},
  journal={Journal of neurobiology},
  year={1996},
  volume={30 2},
  pages={293-302}
}
The neuromuscular junction is a plastic structure and is constantly undergoing changes as the nerve terminals that innervate the muscle fiber extend and retract their processes. In vivo observations on developing mouse neuromuscular junctions revealed that prior to the retraction of a nerve terminal the acetylcholine receptors (AChRs) under that nerve terminal disperse. Agrin is a protein released by nerve terminals that binds to synaptic basal lamina and directs the aggregation of AChRs and… CONTINUE READING