Anti-actin IgA antibodies in severe coeliac disease.

@article{Granito2004AntiactinIA,
  title={Anti-actin IgA antibodies in severe coeliac disease.},
  author={A Granito and Paolo Muratori and Fabio Cassani and Georgios M Pappas and Luigi Muratori and Daniela Agostinelli and Lorenza Veronesi and Roberto Bortolotti and Nunzio Petrolini and FrancescoB. Bianchi and Umberto Volta},
  journal={Clinical and experimental immunology},
  year={2004},
  volume={137 2},
  pages={
          386-92
        }
}
Anti-actin IgA antibodies have been found in sera of coeliacs. Our aim was to define the prevalence and clinical significance of anti-actin IgA in coeliacs before and after gluten withdrawal. One hundred and two biopsy-proven coeliacs, 95 disease controls and 50 blood donors were studied. Anti-actin IgA were evaluated by different methods: (a) antimicrofilament positivity on HEp-2 cells and on cultured fibroblasts by immunofluorescence; (b) anti-actin positivity by enzyme-linked immuosorbent… CONTINUE READING
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