Anti-Xa stability of diluted enoxaparin for use in pediatrics.

  title={Anti-Xa stability of diluted enoxaparin for use in pediatrics.},
  author={William E. Dager and Robert C Gosselin and Jeffery H King and Cinda L Christensen and John T. Owings and Edward C. Larkin},
  journal={The Annals of pharmacotherapy},
  volume={38 4},
BACKGROUND The use of enoxaparin in low-weight pediatric patients is becoming common practice. Anti-Xa stability of unit-dose syringes prepared after dilution beyond one day is presently unknown. OBJECTIVE To evaluate the anti-Xa stability of diluted enoxaparin stored in glass vials and tuberculin syringes. METHODS Four separate batches of enoxaparin were diluted with sterile water to a final concentration of 20 mg/mL (2000 IU/mL) and aliquoted into plastic 1-mL syringes containing 6 mg (0… CONTINUE READING
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