Anti-VEGF-Induced Hypertension: a Review of Pathophysiology and Treatment Options.

  title={Anti-VEGF-Induced Hypertension: a Review of Pathophysiology and Treatment Options.},
  author={Bryan J. Brinda and Federico Viganego and Teresa T. Vo and Dawn E Dolan and Michael G Fradley},
  journal={Current treatment options in cardiovascular medicine},
  volume={18 5},
OPINION STATEMENT Abnormal intracellular signaling has been implicated in the development of many different types of cancer. Therapies targeting these abnormal pathways have revolutionized the treatment of many malignancies leading to significantly improved outcomes and survival. Despite these advances, cardiovascular toxicity is a frequently reported complication. Angiogenesis is the physiologic process of new blood vessel development and can be dysregulated in some forms of cancer. VEGF… CONTINUE READING
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