Anti-U1 RNP antibodies in cerebrospinal fluid are associated with central neuropsychiatric manifestations in systemic lupus erythematosus and mixed connective tissue disease.

Abstract

OBJECTIVE To determine the significance of anti-U1 RNP antibodies in the cerebrospinal fluid (CSF) of patients with systemic lupus erythematosus (SLE) or mixed connective tissue disease (MCTD) who have central neuropsychiatric SLE (NPSLE). METHODS The frequency of antinuclear antibodies including anti-U1 RNP antibodies in the sera and CSF of 24 patients… (More)
DOI: 10.1002/art.27700

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