Anti-Trypanosoma cruzi immunoglobulin G1 can be a useful tool for diagnosis and prognosis of human Chagas' disease.

@article{Cordeiro2001AntiTrypanosomaCI,
  title={Anti-Trypanosoma cruzi immunoglobulin G1 can be a useful tool for diagnosis and prognosis of human Chagas' disease.},
  author={Francesca Cordeiro and Olindo Assis Martins-Filho and Manoel Ot{\'a}vio da Costa Rocha and Sheila Jorge Adad and Rodrigo Corr{\^e}a-Oliveira and Alvaro Jos{\'e} Romanha},
  journal={Clinical and diagnostic laboratory immunology},
  year={2001},
  volume={8 1},
  pages={
          112-8
        }
}
Two functionally distinct antibodies, categorized as conventional serology antibodies (CSA) and lytic antibodies (LA) have been described in Chagas' disease, based on their ability to bind to fixed epimastigotes (EPI) or live trypomastigotes (TRYPO), respectively. In this study, the profile of immunoglobulin G (IgG) subclasses of CSA and LA were analyzed by flow cytometry using serum samples from chronic chagasic patients with the indeterminate (IND), cardiac (CARD), and digestive (DIG… CONTINUE READING

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