Anti-Toxoplasma Activity of 2-(Naphthalene-2-γlthiol)-1H Indole

  title={Anti-Toxoplasma Activity of 2-(Naphthalene-2-γlthiol)-1H Indole},
  author={Qasem Asgari and Hossein Keshavarz and Mostafa Rezaeian and Hossein Sadeghpour and Ramin Miri and Mohammad Hossein Motazedian},
  booktitle={Iranian journal of parasitology},
BACKGROUND This study was undertaken to evaluate the viability, infectivity and immunity of Toxoplasma gondii tachyzoites exposed to 2-(naphthalene-2-ylthio)-1H-indole. METHODS Tachyzoites of RH strain were incubated in various concentrations of 2-(naphthalene-2-ylthio)-1H-indole (25-800 μM) for 1.5 hours. Then, they were stained by PI and analyzed by Fluorescence-activated cell sorting (FACS). To evaluate the infectivity, the tachyzoites exposed to the different concentrations of the… CONTINUE READING