Anti TNF-α in refractory Takayasu's arteritis: cases series and review of the literature.

@article{Comarmond2012AntiTI,
  title={Anti TNF-α in refractory Takayasu's arteritis: cases series and review of the literature.},
  author={Clo{\'e} Comarmond and Emmanuel Plaisier and Karine Y Dahan and Tristan Mirault and Joseph Emmerich and Zahir Amoura and Patrice Cacoub and David Saadoun},
  journal={Autoimmunity reviews},
  year={2012},
  volume={11 9},
  pages={678-84}
}
Takayasu arteritis (TA) is a rare large vessels vasculitis. Conventional therapy consists of glucocorticoids which may be associated with other immunosuppressive drugs. However, some patients fail to achieve remission with conventional treatment. The use of anti-tumor necrosis factor-α (TNF-α) in patients with difficult to treat TA could be useful. We report here the main characteristics, treatment and outcome of 84 patients (5 personal cases and 79 patients from the literature) with refractory… CONTINUE READING