Anti-Sm and anti-RNP antibodies

@article{Migliorini2005AntiSmAA,
  title={Anti-Sm and anti-RNP antibodies},
  author={Paola Migliorini and Chiara Baldini and Valeria Rocchi and Stefano Bombardieri},
  journal={Autoimmunity},
  year={2005},
  volume={38},
  pages={47 - 54}
}
Among anti-nuclear antibodies, anti-Sm and anti-RNP antibodies are of the utmost importance in clinical practice. Anti-Sm antibodies are directed against 7 proteins (B/B′, D1, D2, D3, E, F, G) that constitute the common core of U1, U2, U4 and U5 small nuclear ribonucleoprotein (snRNP) particles; B/B′, D1 and D3 are more frequently targeted. Anti-RNP antibodies react with proteins (70 Kd, A, C) that are associated with U1 RNA and form U1snRNP. Anti-Sm and anti-RNP antibodies are directed towards… 
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TLDR
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TLDR
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TLDR
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