Anti -Plasmodium falciparum activity of Aloe dawei and Justicia betonica

@article{Bbosa2013AntiF,
  title={Anti -Plasmodium falciparum activity of Aloe dawei and Justicia betonica},
  author={Godfrey Sande Bbosa and David B. Kyegombe and Aloysius Lubega and Nathan Lubowa Musisi and Jasper Ogwal-Okeng and Olwa Odyek},
  journal={African Journal of Pharmacy and Pharmacology},
  year={2013},
  volume={7},
  pages={2258-2263}
}
Malaria is a fatal disease caused by different Plasmodium species of parasites and has remained the major killer of humans worldwide especially the children under five years of age and pregnant women. In this study, the anti-Plasmodia activities of the crude leaf ether extracts of Aloe dawei (AD) and Justicia betonica (JB) on Plasmodium falciparum were investigated, with chloroquine diphosphate as a positive control. The results showed that ether extracts of JB had EC50 of 13.36 (95% CI: 8.032… 

Figures and Tables from this paper

Evaluation of Antimalarial Activity of the Leaf Latex and TLC Isolates from Aloe megalacantha Baker in Plasmodium berghei Infected Mice

The present study supports the traditional claim of the plant Aloe megalacantha for the treatment of malaria by observing parasite suppression of leaves latex and isolates and increased the survival time of Plasmodium berghei infected mice as compared to the negative control.

A Review on Antimalarial Activities of Aloe species Extracts

Considering that natural molecules have acted as natural templates in the development of antimalarial agents, it is encouraged to investigate further analyses into Aloe constituents and their values against malaria.

In V itro S creening of Antiplasmodium Activity of Momordica C harantia

Extracts/ fractions of the fruit coat of Momordica charantia, (common name; bitter melon, Balsam) were tested in-vitro for its antiplasmodial activity and only chloroform fraction from the crude extract had shown good antiplaModial activity.

In vitro antimalarial activity of selected medicinal plants native to Tigray region of Ethiopia

BackgroundVarious medicinal plants are used as alternative remedies for the management of malaria, an important infectious disease responsible for around 228 million cases and 405,000 deaths

Antimalarial Plants Used across Kenyan Communities

  • Timothy Omara
  • Biology
    Evidence-based complementary and alternative medicine : eCAM
  • 2020
The study highlighted a rich diversity of indigenous antimalarial plants with equally divergent herbal remedy preparation and use pattern in Kenya, which could be potential sources of antimalaria remedies.

Antimalarial Activity of the Chemical Constituents of the Leaf Latex of Aloe pulcherrima Gilbert and Sebsebe

The results indicate that both the leaf latex of A. pulcherrima and its two major constituents are endowed with antiplasmodial activities, which support the traditional use of the leaves of the plant for the treatment of malaria.

Phytochemical and Pharmacological Profile of Justicia gendarussa Burm f. - review

This review will focus on the phytochemical constituents isolated from the plants and phytopharmacological properties of different parts of Justicia gendarussa.

Overview of the Justicia Genus: Insights into Its Chemical Diversity and Biological Potential

A review of the biological activities of plant extracts and isolated chemical constituents of Justicia (ACANTHACEAE), identified in the period from May 2011 to August 2022, points toward the development of new phytomedicines.

References

SHOWING 1-10 OF 32 REFERENCES

Sub-Saharan Rubiaceae: a review of their traditional uses, phytochemistry and biological activities.

Evidence that great attention has been paid to species such as Nauclea latifolia, Morinda lucida, Mitragyna inermis and Crossopteryx febrifuga since none of these plants has been systematically investigated for its biochemical composition is reported.

In Vitro Chloroquine Resistance in Plasmodium falciparum Isolates from Tertiary Care Hospital

The emergence of chloroquine (CQ) resistance pattern in Aligarh isolates increases and antimalarial agents should be used with caution; monotherapies should be avoided.

Plants used to treat malaria in Nyakayojo sub-county, western Uganda.

Qualitative phytochemical screening and in vitro antimicrobial effects of methanol stem bark extract of Ficus thonningii (Moraceae).

The methanolic stem bark extract of Ficus thonningii was subjected to preliminary phytochemical screening and in vitro antimicrobial tests and the extracts showed varied inhibitory activity against the organisms studied.

Medicinal plants used in traditional treatment of malaria in Cameroon

In order to fight against malaria in Cameroon, an ethnobotanical survey of medicinal plants was conducted in the town of Maroua, Far North Region of Cameroon from 5th to 30th December 2009 with 800

Traditional herbal medicines for malaria

Traditional medicines have been used to treat malaria for thousands of years and are the source of the two main groups (artemisinin and quinine derivatives) of modern antimalarial drugs. With the

Review of Significant Trade East African Aloes

  • 2004
There are approximately 360 species and subspecies in the succulent plant genus Aloe, distributed in Africa, the Arabian Peninsula and certain islands of the Indian Ocean. In East Africa, as defined

Malaria misdiagnosis in Uganda – implications for policy change

To address malaria misdiagnosis, Uganda's policy shift from presumptive to parasitological diagnosis should encompass introduction of malaria rapid diagnostic tests and substantial strengthening of malaria microscopy.