Corpus ID: 54663262

Anti-Paraflagellar Rodc Antibodies Inhibit the In-Vitro Growth of Trypanosoma Brucei Brucei

@article{Mukisa2018AntiParaflagellarRA,
  title={Anti-Paraflagellar Rodc Antibodies Inhibit the In-Vitro Growth of Trypanosoma Brucei Brucei},
  author={Ambrose Mukisa and C. Aguttu and G. Lubega and J. Kyambadde and V. Alibu and P. Vuzi},
  journal={American Scientific Research Journal for Engineering, Technology, and Sciences},
  year={2018},
  volume={40},
  pages={186-197}
}
Paraflagellar rod (PFR), a conserved structure expressed in all lifecycle stages of the order kinetoplasida except in the amastigotes is vital for the parasites survival. In T.b.brucei , the PFR protein has two major components, PFRc and PFRa with molecular mass 73kDa and 68kDa respectively. Experimental evidences implicate the PFR protein as a highly immunogenic and protective antigen. However, its immunogenic properties underlying its suitability as vaccine candidate has not been adequately… Expand

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