Anti-PMP22 antibodies in patients with inflammatory neuropathy.

  title={Anti-PMP22 antibodies in patients with inflammatory neuropathy.},
  author={Carolyn M Gabriel and Norman A. Gregson and Richard A. C. Hughes},
  journal={Journal of neuroimmunology},
  volume={104 2},
An experimental model of inflammatory radiculoneuropathy is induced by immunising rats with peripheral myelin protein 22 (PMP22). We have investigated whether PMP22 may be important in inducing human inflammatory neuropathy. We examined sera of patients with Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), other neuropathies (ONP) and normal controls for IgM and IgG antibodies against PMP22 by ELISA (against synthetic PMP22 extracellular peptide… CONTINUE READING
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