Anti-P-glycoprotein conjugated nanoparticles for targeting drug delivery in cancer treatment.

@article{Iangcharoen2011AntiPglycoproteinCN,
  title={Anti-P-glycoprotein conjugated nanoparticles for targeting drug delivery in cancer treatment.},
  author={Pantiwa Iangcharoen and Wanisa Punfa and Supachai Yodkeeree and Watchara Kasinrerk and Chadarat Ampasavate and Songyot Anuchapreeda and Porn-ngarm Limtrakul},
  journal={Archives of pharmacal research},
  year={2011},
  volume={34 10},
  pages={1679-89}
}
Targeting therapeutics to specific sites can enhance the efficacy of drugs, reduce required doses as well as unwanted side effects. In this work, using the advantages of the specific affinity of an immobilized antibody to membrane P-gp in two different nanoparticle formulations were thus developed for targeted drug delivery to multi-drug resistant cervical… CONTINUE READING