Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis

@article{Pevzner2011AntiLRP4AI,
  title={Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis},
  author={Alexandra Pevzner and Benedikt Schoser and Katja Peters and Nicoleta-Carmen Cosma and Andromachi Karakatsani and Berthold Schalke and Arthur Melms and Stephan Kr{\"o}ger},
  journal={Journal of Neurology},
  year={2011},
  volume={259},
  pages={427-435}
}
Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic transmission at the neuromuscular junction causing fluctuating muscle weakness with a decremental response to repetitive nerve stimulation or altered jitter in single-fiber electromyography (EMG). Approximately 80% of all myasthenia gravis patients have autoantibodies against the nicotinic acetylcholine receptor in their serum. Autoantibodies against the tyrosine kinase muscle-specific kinase (MuSK) are… CONTINUE READING
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