Anti-LGI1-associated cognitive impairment: Presentation and long-term outcome.

  title={Anti-LGI1-associated cognitive impairment: Presentation and long-term outcome.},
  author={Helena Ari{\~n}o and Tha{\'i}s Armangu{\'e} and Mar Petit-Pedrol and Lidia Sabater and Eugenia Mart{\'i}nez-Hern{\'a}ndez and Makoto Hara and Eric Lancaster and Albert Saiz and Josep Dalmau and Francesc Graus},
  volume={87 8},
OBJECTIVE We investigated a series of patients with LGI1 antibody (Ab)-related cognitive deterioration to determine the clinical presentation, long-term outcome, and LGI1 Ab evolution. METHODS We retrospectively analyzed the clinical information of 76 patients with LGI1 Ab-related cognitive deterioration. Presenting syndromes were classified as limbic encephalitis (LE), non-LE, or encephalopathy (normal MRI and no CSF pleocytosis). Frequency of relapses and clinical outcome were assessed in… CONTINUE READING
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