Anti-Jo-1 antibody-positive patients show a characteristic necrotizing perifascicular myositis.

@article{MescamMancini2015AntiJo1AP,
  title={Anti-Jo-1 antibody-positive patients show a characteristic necrotizing perifascicular myositis.},
  author={L{\'e}naig Mescam-Mancini and Yves F Allenbach and Baptiste Hervier and Herv{\'e} Devilliers and Kuberaka Mariampillay and Odile Dubourg and Thierry Maisonobe and Romain Kroum Gherardi and Paulette Mezin and Corinna Preusse and Werner Stenzel and Olivier Benveniste},
  journal={Brain : a journal of neurology},
  year={2015},
  volume={138 Pt 9},
  pages={2485-92}
}
Idiopathic inflammatory myopathies can be classified as polymyositis, dermatomyositis, immune-mediated necrotizing myopathy, sporadic inclusion body myositis or non-specific myositis. Anti-Jo-1 antibody-positive patients are assigned to either polymyositis or dermatomyositis suggesting overlapping pathological features. We aimed to determine if anti-Jo-1 antibody-positive myopathy has a specific morphological phenotype. In a series of 53 muscle biopsies of anti-Jo-1 antibody-positive patients… CONTINUE READING