Anti-Inflammatory and Pro-apoptotic Effects of Curcumin and Resveratrol on the Human Lung Fibroblast Cell Line MRC-5

  title={Anti-Inflammatory and Pro-apoptotic Effects of Curcumin and Resveratrol on the Human Lung Fibroblast Cell Line MRC-5},
  author={Burkhard Kloesch and Elisabeth Dietersdorfer and Silvia Loebsch and Guenter Steiner},
  journal={Alternative \& Integrative Medicine},
Background: The naturally occuring polyphenols curcumin and resveratrol are considered to be powerful antioxidants and anti-inflammatory compounds and both inhibit the proliferation of different types of cancer cells. In the present study, we investigated possible anti-inflammatory and pro-apoptotic effects of curcumin and resveratrol on the human lung fibroblast cell line MRC-5. Methods: MRC-5 cells were stimulated for 6 h with interleukin (IL)-1β or phorbol 12- myristate 13-acetate (PMA) in… 

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