Anti-Inflammatory Treatment With Colchicine in Acute Myocardial Infarction: A Pilot Study.

  title={Anti-Inflammatory Treatment With Colchicine in Acute Myocardial Infarction: A Pilot Study.},
  author={Spyridon G Deftereos and Georgios Giannopoulos and Christos Angelidis and Nikolaos Alexopoulos and Gerasimos S. Filippatos and Nikolaos Papoutsidakis and George Sianos and John A. Goudevenos and Dimitrios Alexopoulos and Vlasios N Pyrgakis and Michael W. Cleman and Antonis S Manolis and Dimitris Tousoulis and John P. Lekakis},
  volume={132 15},
BACKGROUND Inflammatory processes have been identified as key mediators of the deleterious effects of ischemia/reperfusion in ST-segment-elevation myocardial infarction. Colchicine is a substance with potent anti-inflammatory properties, suitable for safe use in patients with cardiovascular disease. The purpose of this study was to test the hypothesis that a short course of colchicine treatment could lead to reduced infarct size. METHODS AND RESULTS Patients presenting with ST-segment… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 48 references

Effect of cyclosporine on reperfusion injury in acute myocardial infarction.

The New England journal of medicine • 2008
View 4 Excerpts
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S van Diepen, LK Newby, +14 authors P Theroux
Int J Cardiol. 2013;168:2127-2133. by gest on A ril 14, • 2017
View 1 Excerpt

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Am J Cardiol • 2017
View 3 Excerpts

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JACC Heart Fail • 2017
View 1 Excerpt

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