Anti-Inflammatory Effects of Pravastatin on Helicobacter Pylori-Induced Gastritis in Mice

@article{Yamato2006AntiInflammatoryEO,
  title={Anti-Inflammatory Effects of Pravastatin on Helicobacter Pylori-Induced Gastritis in Mice},
  author={Masanori Yamato and Toshio Watanabe and Kazuhide Higuchi and Koichi Taira and Tetsuya Tanigawa and Masatsugu Shiba and K Tominaga and Yasuhiro Fujiwara and Nobuhide Oshitani and Koji Takeuchi and Tetsuo Arakawa},
  journal={Digestive Diseases and Sciences},
  year={2006},
  volume={52},
  pages={2833-2839}
}
Pravastatin, an HMG-CoA reductase inhibitor, exerts anti-inflammatory effects via several mechanisms including induction of endothelial nitric oxide synthase (eNOS). We investigated the effect of pravastatin on Helicobacter pylori-induced gastritis in mice. Mice with or without H. pylori infection received intraperitoneal pravastatin daily for 1 week… CONTINUE READING