Anti-Inflammatory Effects of Poly-γ-Glutamic Acid on DNCB-Induced Allergic Contact Dermatitis in Dogs

@inproceedings{Kim2012AntiInflammatoryEO,
  title={Anti-Inflammatory Effects of Poly-γ-Glutamic Acid on DNCB-Induced Allergic Contact Dermatitis in Dogs},
  author={Hyun-gon Kim and Kil-Soo Kim and Tae-ho Oh},
  year={2012}
}
Allergic contact dermatitis (ACD) is an inflammatory skin disease and regarded as a prototype of T-cell mediated delayed-type hypersensitivity reactions. Poly-γ-glutamic acid (PGA) is a biodegradable polymer that is produced by Bacillus subtilis. This study was performed to assess the effects of PGA in a canine model of ACD. ACD was induced on the back of dogs induced by sensitization and repeated application by 2,4-dinitro-1-chlorobenzene (DNCB). Topical treatment of PGA was applied once a day… CONTINUE READING