Anti-HPA-3A induces severe neonatal alloimmune thrombocytopenia.

Abstract

OBJECTIVE Fetal and neonatal alloimmune thrombocytopenia (AIT) caused by feto-maternal incompatibility at the HPA-1a (PLA-1) locus is well characterized. Alloimmunization and disease caused by HPA-3a is rare. STUDY DESIGN We conducted a retrospective analysis of all known cases of AIT caused by HPA-3a incompatibility identified at 3 major reference… (More)

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