Anti-HBV Activities of Three Compounds Extracted and Purified from Herpetospermum Seeds

@article{Gong2016AntiHBVAO,
  title={Anti-HBV Activities of Three Compounds Extracted and Purified from Herpetospermum Seeds},
  author={P. Gong and Zhi-Xiang Yuan and J. Gu and Rui Tan and Jia-chuan Li and Yan Ren and Sha Hu},
  journal={Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry},
  year={2016},
  volume={22}
}
  • P. Gong, Zhi-Xiang Yuan, +4 authors Sha Hu
  • Published 2016
  • Chemistry, Medicine
  • Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
The goal of this research was to evaluate the anti-hepatitis B virus (HBV) activities of three compounds extracted and purified from Herpetospermum seeds (HS) on HepG2.2.15 cells. Herpetin (HPT), herpetone (HPO), and herpetfluorenone (HPF) were isolated from HS and identified using HR-ESI-MS and NMR. Different concentrations of the drugs were added to the HepG2.2.15 cells. Cell toxicity was observed with an MTT assay, cell culture supernatants were collected, and HBsAg and HBeAg were detected… Expand
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