Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity.

@article{Ingram2010AntiEBNA1II,
  title={Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity.},
  author={Gillian Ingram and Joachim Jakob Bugert and Sam Loveless and Neil P. Robertson},
  journal={European journal of neurology},
  year={2010},
  volume={17 11},
  pages={
          1386-9
        }
}
BACKGROUND Sero-epidemiological studies have demonstrated the association between multiple sclerosis (MS) and prior Epstein-Barr virus (EBV) infection. It has been hypothesized that intermittent peripheral EBV reactivation may drive continuing central inflammation. Recent investigation has shown significant differences in median serum levels of anti-EBV nuclear antigen-1 (EBNA-1) IgG between disease subgroups and positive correlation with disease activity reflected by number of Gd-enhancing… CONTINUE READING
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EpsteinBarr virus and disease activity in multiple sclerosis

  • D Buljevac, GJ van Doornum, HZ Flach
  • J Neurol Neurosurg Psychiatry
  • 2005

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