• Corpus ID: 13860054

Anti Alzheimer ’ s Disease Related Activities of Israeli Medicinal Plants

@inproceedings{Tsalkovich2015AntiA,
  title={Anti Alzheimer ’ s Disease Related Activities of Israeli Medicinal Plants},
  author={Lea Tsalkovich and Sarah Sallon and Helena M. Paavilainen and Hanna Rosenmann},
  year={2015}
}
Medicinal plants may provide a potential source of therapeutic agents against Alzheimer’s-disease (AD) and other dementias. In the current study medical plants with an historical/traditional use for improving memory were evaluated for anti-AD activity. Plants were collected mainly from wild species growing in Israel and tested for their protective properties against toxicity of amyloid-beta (Aβ) and a decrease in its secretion by neuronal cells (SHSY5Y and PC12). Of 20 plants tested, 5 plants… 

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References

SHOWING 1-10 OF 35 REFERENCES

Evaluating Medicinal Plants for Anticancer Activity

Plant extract 5 (Urtica membranacea) showed particularly strong anticancer capabilities since it inhibited actual tumor progression in a breast adenocarcinoma mouse model.

The Herbal Preparation Padma® 28 Protects Against Neurotoxicity in PC12 Cells

The study investigated the protective effect of Padma 28 and of certain polyphenols on the neurotoxicity of PC12 cells induced by the neurotoxins known to be involved in AD, Parkinson's disease, amyotrophic‐lateral‐sclerosis (ALS) and Huntington's disease (HD), and found that the decrease in cell viability induced by each of the toxins was significantly attenuated byPadma 28 treatment.

In vitro antileishmanial, antitumor, cytotoxic activities and phyto-chemical analysis of Citrullus colocynthis fruit extract and its fractions.

Citrullus colocynthis fruits have been widely used in folk medicine for its medicinal properties (Hartwell 1971). In the present study the crude methanolic fruit extract (CME) and its fractions:

The effects of glycosides of cistanche on learning and memory in β-amyloid peptide induced Alzheimers disease in mice and its possible mechanism

GCs significantly improves the ability of learning and memory induced by β-AP in AD mice and its possible mechanism of action may involve: Enhancement of free radical scavengers; inhibition of lipid peroxidation; and inhibition of β- AP precipitation and apoptosis in mice brain cells induced byβ-AP.

Analysis of chemical constituents in Cistanche species.

Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.

Evidence is provided that acteoside inhibits basophilic cell-derived immediate-type and delayed-type allergic reactions, which is the first report describing antiallergic activity of acteooside extracted from CISTANCHE TUBULOSA on Basophilic cells.