Anti-A isoagglutinin as a risk factor for the development of pure red cell aplasia after major ABO-incompatible allogeneic bone marrow transplantation

@article{Lee2000AntiAIA,
  title={Anti-A isoagglutinin as a risk factor for the development of pure red cell aplasia after major ABO-incompatible allogeneic bone marrow transplantation},
  author={J R Lee and K S Lee and Shin-Hee Kim and J S W Lee and S-W Kwon and W C Kim},
  journal={Bone Marrow Transplantation},
  year={2000},
  volume={25},
  pages={179-184}
}
Delayed erythropoiesis and pure red cell aplasia (PRCA) have been reported after major ABO-incompatible BMT. We attempted to find risk factors for the development of PRCA in 27 patients who underwent major ABO-incompatible BMT. In all patients, the donor marrow was depleted of RBCs before infusion. In 22 patients, isoagglutinins were determined until they disappeared. In eight (29.6%) out of 27 patients, bone marrow examination following BMT showed the findings of PRCA. We analyzed various… CONTINUE READING
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Trans - fusion of donor - type red cells as a single preparative treatment for bone marrow transplants with major ABO incompatibility

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