Anti-αvβ3 antibody guided three-step pretargeting approach using magnetoliposomes for molecular magnetic resonance imaging of breast cancer angiogenesis

@inproceedings{Yan2013Antiv3AG,
  title={Anti-αvβ3 antibody guided three-step pretargeting approach using magnetoliposomes for molecular magnetic resonance imaging of breast cancer angiogenesis},
  author={Chenggong Yan and Yuankui Wu and Jie Feng and Wufan Chen and Xiang Liu and Peng Hao and Ruimeng Yang and Juan Zhang and Bingquan Lin and Yikai Xu and Ruiyuan Liu},
  booktitle={International journal of nanomedicine},
  year={2013}
}
PURPOSE Pretargeting of biomarkers with nanoparticles in molecular imaging is promising to improve diagnostic specificity and realize signal amplification, but data regarding its targeting potential in magnetic resonance (MR) imaging are limited. The purpose of this study was to evaluate the tumor angiogenesis targeting efficacy of the anti-αvβ3 antibody guided three-step pretargeting approach with magnetoliposomes. METHODS Polyethylene glycol-modified and superparamagnetic iron oxide… CONTINUE READING

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