Anti‐ulcer drugs promote IgE formation toward dietary antigens in adult patients

@article{Untersmayr2005AntiulcerDP,
  title={Anti‐ulcer drugs promote IgE formation toward dietary antigens in adult patients},
  author={E. Untersmayr and N. Bakos and I. Schoell and M. Kundi and F. Roth-Walter and K. Szalai and A. Riemer and H. Ankersmit and O. Scheiner and G. Boltz-nitulescu and E. Jensen-Jarolim},
  journal={The FASEB Journal},
  year={2005},
  volume={19}
}
  • E. Untersmayr, N. Bakos, +8 authors E. Jensen-Jarolim
  • Published 2005
  • Medicine
  • The FASEB Journal
  • Recently, we have demonstrated that anti‐ulcer drugs, such as H2‐receptor blockers and proton pump inhibitors, promote the development of immediate type food allergy toward digestionlabile proteins in mice. The aim of this study was to examine the allergological relevance of these findings in humans. In an observational cohort study, we screened 152 adult patients from a gastroenterological outpatient clinic with negative case histories for atopy or allergy, who were medicated with H2‐receptor… CONTINUE READING
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    References

    SHOWING 1-10 OF 39 REFERENCES
    Antacid medication inhibits digestion of dietary proteins and causes food allergy: a fish allergy model in BALB/c mice.
    • 233
    Stability of food allergens to digestion in vitro
    • 824
    Allergies to Cross-Reactive Plant Proteins
    • T. Yagami
    • Medicine
    • International Archives of Allergy and Immunology
    • 2002
    • 63
    • PDF
    Allergen mimotopes in food enhance type I allergic reactions in mice
    • 64
    Prevalence of sensitization to food allergens in adult Swedes.
    • 88
    Digestibility of allergens extracted from natural rubber latex and vegetable foods.
    • 109
    Infective gastroenteritis and its relationship to reduced gastric acidity.
    • G. C. Cook
    • Medicine
    • Scandinavian journal of gastroenterology. Supplement
    • 1985
    • 80
    Peptic ulcer: the many proteinases of aggression.
    • 102