Anti‐diabetic effect of Nelumbo nucifera (Gaertn): Part I preliminary studies in rabbits

  title={Anti‐diabetic effect of Nelumbo nucifera (Gaertn): Part I preliminary studies in rabbits},
  author={J. C. Huralikuppi and A. B. Christopher and P. M. Stephen},
  journal={Phytotherapy Research},
Nelumbo nucifera Gaertn, an Indian aquatic herb, has been studied for its potential utility in the treatment of Diabetes mellitus. The powdered sun‐dried flowers (test drug), as well as the aqueous and alcoholic extracts of these, produced significant hypoglycaemia in fasting normal albino rabbits. There was no significant difference in the activities of 1000 mg/kg of the test drug and equivalent amounts of the extracts; the effect was approximately 50% of that produced by 250 mg/kg of… 

Antidiabetic effect of Nelumbo nucifera (Gaertn) extract: Part II

In vitro studies with rat hemidiaphragms revealed that test drug treatment of donor animals significantly enhanced the effect of insulin, and improvement of glucose tolerance may also be due to increased peripheral glucose utilization caused by increased sensitivity of skeletal muscles to endogenous insulin.


  • Medicine, Chemistry
  • 2014
Hydroethanolic NNFE treated rats showed significant results in comparison with atorvastatin (positive control) treated rats and improved Lipid Profile, which improves total cholesterol and triglycerides level.

Development, evaluation and quality control of new antidiabetic ayurvedic polyherbal combination

Study showed that FB was found extremely significant in reducing the blood glucose level as compared to all others, and was proved to be most beneficial combination.

Antioxidant and Antidiabetic Activities of Fresh Aqueous Pink Petals of Indian Lotus-Nelumbo nucifera Gaertn.

The antibacterial activity of fresh aqueous pink petals of Nelumbo nucifera showed maximum zone of inhibition of 14 mm for B. subtilis and minimum zone of inhibited of 10 mm for E. coli at 375 μg/mL concentration.

Nelumbo Nucifera (Lotus): A Review on Ethanobotany, Phytochemistry and Pharmacology

The present review is an effort to consolidate traditional, ethnobotanic, phytochemical and pharmacological information available on N.nucifera to verify it's utility through scientific pharmacological screenings.

A brief review on pharmaceutical uses of Nelumbo nucifera

This review is to combine pharmaceutical information on Nelumbo nucifera with physiological benefits of the plant, which has antifertility, antianalgesic properties and as well as does gastrointestinal regulation.

A review on medicinal plants with antidiabetic activity

The large number of plants described in this review clearly demonstrated the importance of herbal plants in the treatment of diabetes, and the effects of these plants may delay the development of diabetic complications and correct the metabolic abnormalities.

Ethno-medicinal uses and pharmacological activities of lotus (Nelumbo nucifera)

The current review highlights the importance of Nelumbo nucifera in traditional medicines and its pharmacological activities in Kashmir.

A Review of Phytopharmacological Studies on Some Common Flowers

  • Biology
  • 2016
Here the authors focus on 10 flowers which are popular remedies for a host of diseases and in which significant phytochemical and pharmacological studies are carried out or are going on.

Medicinal Plants: A Source of Antidiabetic Drugs

This study concluded that the profiles of plant species were generally used for treatment of disease and having antidiabetic properties can be an effective source for the development of safer oral hypoglycemic agents.



Hypoglycemic activity of polypeptide-p from a plant source.

A hypoglycemic peptide, Polypeptide-p, has been isolated from fruit, seeds, and tissue of Momordica charantia Linn (bitter gourd). Amino acid analysis indicates a minimum molecular weight of

Observations on some conditions affecting the rate of hormone output by the suprarenal cortex

  • M. Vogt
  • Biology, Medicine
    The Journal of physiology
  • 1944
The effect of various factors on the rate of this secretion of cortical hormone is dealt with, mainly concerned with the influence of adrenaline and of splanchnic stimulation.