Anthrax vaccine antigen-adjuvant formulations completely protect New Zealand white rabbits against challenge with Bacillus anthracis Ames strain spores.

@article{Peachman2012AnthraxVA,
  title={Anthrax vaccine antigen-adjuvant formulations completely protect New Zealand white rabbits against challenge with Bacillus anthracis Ames strain spores.},
  author={Kristina K. Peachman and Qin Li and Gary R Matyas and Sathish Bhadravati Shivachandra and Julie A. Lovchik and Rick C Lyons and Carl R. Alving and Venigalla Rao and Mangala Rao},
  journal={Clinical and vaccine immunology : CVI},
  year={2012},
  volume={19 1},
  pages={11-6}
}
In an effort to develop an improved anthrax vaccine that shows high potency, five different anthrax protective antigen (PA)-adjuvant vaccine formulations that were previously found to be efficacious in a nonhuman primate model were evaluated for their efficacy in a rabbit pulmonary challenge model using Bacillus anthracis Ames strain spores. The vaccine… CONTINUE READING