Anthraquinones from the roots of Knoxia valerianoides

@article{Zhao2011AnthraquinonesFT,
  title={Anthraquinones from the roots of Knoxia valerianoides},
  author={F. Zhao and S. Wang and Sheng Lin and Chenggen Zhu and S. Yuan and Xiaoyu Ding and Zheng-gang Yue and Yang Yu and Bo Liu and X. Wu and Qi Hou and J. Shi},
  journal={Journal of Asian Natural Products Research},
  year={2011},
  volume={13},
  pages={1023 - 1029}
}
  • F. Zhao, S. Wang, +9 authors J. Shi
  • Published 2011
  • Chemistry, Medicine
  • Journal of Asian Natural Products Research
Five new 9,10-anthraquinones (1–5) were isolated from an ethanol extract of the roots of Knoxia valerianoides. Their structures including absolute configuration of 1 were determined by spectroscopic analysis. Compounds 4 and 5 showed moderate activity against nitrogen oxide production in macrophages induced by lipopolysaccharide, at 10− 5 M, with inhibition ratios of 50.4 ± 3.6 and 41.7 ± 2.1%, respectively. 
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