Anthraquinones and Iridoids from Morinda officinalis

  title={Anthraquinones and Iridoids from Morinda officinalis},
  author={Fei Yang and Yan-fang Su and Ze-Qing Zhao and Meng Que and Tianxiang Li and Xiumei Gao},
  journal={Chemistry of Natural Compounds},
A new anthraquinone, 2,5,8-trihydroxy-1-methoxyanthraquinone (1), was isolated from the roots of Morinda officinalis together with two anthraquinones, 1,4-dihydroxyanthraquinone (2) and anthragallol-1,3-dimethylether (3), and two iridoids, ningpogenin (4) and monotropein methyl ester (5). The structure of 1 was elucidated by spectroscopic methods including 1D, 2D NMR, HR-MS, and IR. This is the first report of compounds 2–5 from the genus Morinda. 

A Review on the Phytochemistry, Pharmacology, Pharmacokinetics and Toxicology of Geniposide, a Natural Product

This review paper aims to provide the researchers with a comprehensive profile of geniposide on its phytochemistry, pharmacology, pharmacokinetics and toxicology in order to highlight some present issues and future perspectives as well as to help develop and utilize this iridoid glycoside more efficiently and safely.

Progress of the components and biological activities of Morinda officinalis How

The Morinda officinalis How is “one of the top four south authentic traditional Chinese medicines”, widely distributed in South District of China, and widely used for the treatment of sexual impotence, spermatorrhea, irregular menstruation, and female infertility in clinical.

Indian Morinda species: A review

The toxicological studies revealed that higher doses of fruit juice of M. citrifolia for 2 or more months cause toxic effects on liver and kidneys, and M. officinalis root extracts (ethanolic and aqueous) are found fully safe during treatment of diseases.

Characterization and novel Est-SSR marker development of an important Chinese medicinal plant, Morinda officinalis How (Rubiaceae)

Novel EST-SSR markers with high cross-species transferability between M. officinalis and its closely-related species could serve as aids to future studies in genetic diversity, conservation, assisted-selection breeding and genes associated with the medical uses of the genus.

uantitative determination of monotropein in rat plasma and tissue y LC – MS / MS and its application to pharmacokinetic and tissue istribution studies

A selective and sensitive liquid chromatography tandem with mass spectrometry was developed and validated and successfully applied to a pharmacokinetic and tissue distribution study of monotropein in rats.