Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.

@article{Yang2013AnthraquinoneDF,
  title={Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.},
  author={Yang Yang and Yong-ming Yan and Wei Wei and Jie Luo and Lan-sheng Zhang and Xiao-jiang Zhou and Peng-cheng Wang and Yong-xun Yang and Yong-Xian Cheng},
  journal={Bioorganic & medicinal chemistry letters},
  year={2013},
  volume={23 13},
  pages={
          3905-9
        }
}
Two new oxanthrone C-glycosides, patientosides A (14) and B (15), together with three known ones (11-13), were isolated from Rumex patientia. Their structures were identified on the basis of spectroscopic methods. The absolute configuration for 14 and 15 were deduced by analysis of their CD spectra and comparison with those of known similar compounds. Compounds 11-15, and 14 known anthraquinones (1-4, 6-10, 16-20) previously isolated from Rumex nepalensis, Rumex hastatus, and endophytic… CONTINUE READING
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The Genus Rumex: Review of traditional uses, phytochemistry and pharmacology.

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Asphodosides A-E, anti-MRSA metabolites from Asphodelus microcarpus.

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The established rat mesangial cell line (RMC) HBZY-1 was obtained from The Chinese Center for Type Culture Collection (Wuhan, China)

Cell culture, reagents
  • The cells were cultured in DMEM supplemented with 10% fetal calf serum, 2 mM glutamine, 100 U/mL penicillin, and 100 lg/mL streptomycin at 37 C in an atmosphere containing 5% CO2. RMC between passages 3 and 10 Y. Yang et al. / Bioorg. Med. Chem. Lett. 23
  • 2013

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