Anthracycline cardiotoxicity in long-term survivors of childhood cancer
@article{Scully2007AnthracyclineCI, title={Anthracycline cardiotoxicity in long-term survivors of childhood cancer}, author={Rebecca E Scully and Steven E. Lipshultz}, journal={Cardiovascular Toxicology}, year={2007}, volume={7}, pages={122-128} }
Anthracycline chemotherapy is a widely-used and effective treatment for a wide spectrum of childhood cancers. Its use is limited by associated progressive and clinically significant cardiotoxic effects. Onset can be acute, early, or late. While acute onset is rare, long-term survivors have significantly elevated rates of cardiac morbidity and mortality. Major complications include cardiomyopathy, coronary artery disease, and atherosclerosis. Means of prevention and treatment continue to be…
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