Anthelmintic resistance--looking to the future: a UK perspective.

  title={Anthelmintic resistance--looking to the future: a UK perspective.},
  author={Gerald C. Coles},
  journal={Research in veterinary science},
  volume={78 2},
The full extent of anthelmintic resistance in nematodes of farm animals is not known. Resistance can be detected with a faecal egg count reduction test and two in vitro tests, the egg hatch and larval development tests. The sensitivity of these two in vitro tests can be increased by using discriminating doses rather than calculating LD50 values. Only benzimidazole resistance can be detected with PCR based tests because the molecular mechanisms of resistance to levamisole and the macrocyclic… CONTINUE READING

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