Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences.

  title={Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences.},
  author={Jason Pellettieri and Geraldine Seydoux},
  volume={298 5600},
The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes. 

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D. N. Cox, S. A. Seyfried, L. Y. Jan, Y. N. Jan
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Gonczy for illuminating discussions; D. Montell for critical reading

P. We thank
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