Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences.

@article{Pellettieri2002AnteriorposteriorPI,
  title={Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences.},
  author={Jason Pellettieri and Geraldine Seydoux},
  journal={Science},
  year={2002},
  volume={298 5600},
  pages={1946-50}
}
The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes. 

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P. We thank
VOL 298 SCIENCE www.sciencemag.org 1950 P O L A R I T Y • 2002

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