Anterior definitive endoderm from ESCs reveals a role for FGF signaling.

@article{Morrison2008AnteriorDE,
  title={Anterior definitive endoderm from ESCs reveals a role for FGF signaling.},
  author={Gillian M. Morrison and Ifigenia Oikonomopoulou and Rosa Portero Migueles and Shamit Soneji and Alessandra Livigni and Tariq Enver and Joshua M Brickman},
  journal={Cell stem cell},
  year={2008},
  volume={3 4},
  pages={402-15}
}
The use of embryonic stem cell (ESC) differentiation to generate functional hepatic or pancreatic progenitors and as a tool for developmental biology is limited by an inability to isolate in vitro equivalents of regionally specified anterior definitive endoderm (ADE). To address this, we devised a strategy using a fluorescent reporter gene under the transcriptional control of the anterior endoderm marker Hex alongside the definitive mesendoderm marker Cxcr4. Isolation of Hex(+)Cxcr4… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 65 extracted citations

Signaling pathways during maintenance and definitive endoderm differentiation of embryonic stem cells.

The International journal of developmental biology • 2013
View 11 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…